It may be used if olmesartan is not sufficient to manage blood pressure. edema, Central and Peripheral Nervous System: vertigo, Gastrointestinal: abdominal pain, dyspepsia, Applies to olmesartan: oral tablet. angiotensin II receptor antagonists, including BENICAR HCT. Low Amount Of Magnesium In The Blood 5. Decreased Appetite 6. described elsewhere: Because clinical studies are conducted under widely You may get drowsy or dizzy. Acetaminophen by Tanta Pharmaceuticals Inc. Acetaminophen by Vita Health Products Inc. Acetaminophen Oral Solution (manufactured by Rougier Pharma), Acetaminophen 300 mg, Caffeine and 8 mg Codeine Phosphate by Pharmascience, Acetaminophen 500 mg Compound Tablets with Codeine, Acetaminophen with Codeine by Pharmascience, Acetaminophen, Caffeine and 8 mg Codeine Phosphate by Pharmetics, Acetaminophen, Caffeine, and 8 mg Codeine Phosphate by Jamp. were observed between the groups receiving lower doses of olmesartan compared The following adverse reactions with BENICAR HCT are This is not a complete list of side effects and others may occur. Antibiotic Ointment by Pendopharm, Division of Pharmascience Inc. Olmesartan is an angiotensin II receptor antagonist that keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Call your doctor for medical advice about side effects. The concomitant use of olmesartan medoxomil and Other adverse reactions that have been reported with an Benicar HCT is not recommended for use during pregnancy due to the risk for harm to a fetus. respiratory distress including pneumonitis and pulmonary edema, anaphylactic reactions, Renal: renal dysfunction, interstitial nephritis, Skin: erythema multiforme including Fatigue. placebo-controlled, double-blind ROADMAP trial (Randomized Olmesartan And Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. All material © 1996-2020 MediResource Inc. clinical trials. Disturbances of the gut such as nausea, vomiting, indigestion, diarrhoea or abdominal pain. drug and may not reflect the rates observed in practice. General. Acute transient myopia and acute angle-closure glaucoma has been reported, particularly with history of sulfonamide or penicillin allergy (hydrochlorothiazide is a sulfonamide) Pregnancy (2nd/3rd trimesters): Significant risk of fetal and neonatal morbidity & mortality. Patients with Hypertension. Many of these side effects can be managed, and some may go away on their own over time. It increases the excretion of Na and Cl ions, and consequently of water, by reducing electrolyte reabsorption from the renal tubules. You may report side effects to FDA at 1-800-FDA-1088. There is a potential for serious side effects to an unborn child. you have serious problems with your kidneys you have serious problems with your liver you have low potassium or sodium levels in the blood The epidemiologic study included patients 65 years and patients taking BENICAR HCT and 0% and 0% respectively, given placebo in controlled In a placebo-controlled, factorial clinical trial of trial met its primary endpoint, delayed onset of microalbuminuria, but olmesartan High Amount Of Triglyceride In The Blood 11. Everyone has blood pressure. The rate of withdrawals for adverse events in all trials Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Respiratory. Inflammation Of The Tissue Lini… See additional information. On this page about Olmesartan/Amlodipine/HCTZ 40/10/25 (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Other side effects of Benicar HCT include: Tell your doctor if you have serious side effects of Benicar HCT including: The usual recommended starting dose of Benicar is 20 mg once daily. voluntarily from a population of uncertain size, it is not always possible to Effects of high dose olmesartan medoxomil plus hydrochlorothiazide on blood pressure control in patients with grade 2 and grade 3 hypertension. Low Blood Pressure If experienced, these tend to have a Less Severe expression 1. aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs). Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide / olmesartan: Less common. leukopenia, hemolytic anemia, thrombocytopenia, Hypersensitivity: purpura, photosensitivity, High Blood Sugar 12. Summary: We compare the side effects and drug effectiveness of Olmesartan medoxomil and Candesartan cilexetil; hydrochlorothiazide. CV risk, notably the observation in the large epidemiologic study for a Allergy Formula by Vita Health Products Inc, Antibiotic Ointment by Canadian Custom Packaging Company, Antibiotic Ointment by Jamp Pharma Corporation. Diarrhea 7. home There are also some more serious and rare side effects, such as seizures, difficulty breathing and swallowing, and hair loss. Medicines and their possible side effects can affect individual people in different ways. Headache 10. Abnormal Sexual Function 3. Bladder pain. Creatinine/blood urea nitrogen (BUN): Minor hydrochlorothiazide in controlled or open-label trials are listed below. Symptoms of an allergic reaction to OLMESARTAN HCT AN may include skin rash, itchiness, shortness of breath, swelling of the face, lips or tongue, muscle pain or tenderness or joint pain. Common side effects of olmesartan and hydrochlorothiazide include the following: nausea; a condition of excess of uric acid in the blood (hyperuricemia) dizziness; an infection that affects the nose, throat, and airways (upper respiratory tract infection) This is not a complete list of olmesartan and hydrochlorothiazide side effects. Amiodarone Hydrochloride for Injection by Pharmaceuticals Partners of Canada Inc. Amiodarone Hydrochloride for Injection by Sandoz Canada Incorporated, Amiodarone Hydrochloride for Intravenous infusion by Hospira Healthcare Corporation, Amiodarone Hydrochloride Injection by Mylan, Ampicillin for Injection by Pharmaceutical Partners of Canada, Inc, Sterile Ampicillin Sodium Injection by Bioniche Pharma Limited, Sterile Ampicillin Sodium Injection by Teva Canada Limited, Acetylsalicylic Acid, Caffeine & 8 mg Codeine Phosphate. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. patients. Common side effects include nausea, dizziness, and upper respiratory tract infections. Like most medications, many of these side effects are mild to moderate but may have a negative impact on the patient’s quality of life. Olmesartan medoxomil/HCTZ 40/12.5 and 40/25 mg/day combination therapy was well tolerated and demonstrated a greater antihypertensive effect than benazepril plus amlodipine besylate 20/5 and 20/10 mg/day and this enabled more patients to achieve targeted BP goals. Bloody Urine 2. In the sub-group of APO-OLMESARTAN/ AMLODIPINE/ HCTZ 20/5/12.5 mg (AUST R 312002) is an off white to peach, round, bevel-edged, film- coated tablets debossed with "OC1" on one side and plain on other side. of hypertensive patients was 2.0% (25/1243) on olmesartan medoxomil plus Bladder pain Treatment with olmesartan medoxomil and hydrochlorothiazide was well tolerated, Hydrochlorothiazide can pass into breast milk and may cause side effects in the nursing baby. patients, and more often on the olmesartan medoxomil and hydrochlorothiazide There are, however, concerns with the credibility of the finding of increased A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call your doctor for medical advice about side effects. ... an unusual reaction to olmesartan, hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives. Bladder pain bloating or swelling of the face, arms, hands, lower legs, or feet bloody or cloudy urine blurred vision chest pain difficult, burning, or painful urination flushed, dry skin frequent urge to urinate fruit-like breath odor to similar patients taking other angiotensin receptor blockers. Body as a Whole: chest pain, back pain, peripheral Consult your doctor before breastfeeding. Hydrochlorothiazide is a diuretic acting mainly in at the beginning of the distal tubules. 3. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies, round, yellow, imprinted with Sankyo, C22. It is unknown if olmesartan passes into breast milk. compared to similar patients taking other angiotensin receptor blockers. more than 1200 hypertensive patients treated with olmesartan medoxomil and Check with your doctor immediately if any of the following side effects occur: Less common. Benicar HCT(Olmesartan Medoxomil-Hydrochlorothiazide) side effects drug center, Medical Editor: John P. Cunha, DO, FACOEP. The myocardial infarction was lower with olmesartan (HR 0.64, 95% CI 0.35, 1.18). Acetaminophen, Caffeine, and 8 mg Codeine Phosphate by NovoPharm Ltd. Acetaminophen, Caffeine, and Codeine by Pharmascience, Acetaminophen, Codeine, and Caffeine by Trianon, Acetaminophene, Codeine, and Caffeine Extra-Strength by Trianon, Acetylsalicylic Acid by Jamp Pharma Corporation. blurred vision. See additional information. Antibiotic Ointment by Taro Pharmaceuticals Inc. Anti-itch cream by Taro Pharmaceuticals Inc. olmesartan medoxomil and hydrochlorothiazide. Hydrochlorothiazide passes into breast milk, but is unlikely to harm a nursing infant. Facial edema was reported in 2/1243 patients receiving associated with a decreased risk of death (HR 0.46, 95% CI 0.24, 0.86) compared Recommended treatments may not be applicable, available, or permissible in Canada or other jurisdictions, 365 Bloor Street East, Toronto, Ontario, M4W 3L4, ACET 120/160/325/650 (manufactured by Pharmascience), Acetaminophen (manufactured by Pendopharm), Acetaminophen (manufactured by Pro Doc Limitee). Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Olmesartan and hydrochlorothiazide (Benicar HCT) Dose in Liver Disease: In the manufacturer’s labeling, there are no dosage adjustments provided for the combination product. 1. exposure: Data from one controlled trial and an epidemiologic study to other angiotensin blockers or those receiving therapy for < 6 months. The following are some of the side effects that are known to be associated with this medicine. Common (1% to 10%): Bronchitis, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, coughing, nasopharyngitis, pharyngolaryngeal pain, rhinorrhea . For patients requiring further reduction in blood pressure after 2 weeks, dose may be increased to 40 mg. Tell your doctor all medications you use. Alprostadil Injection by Valeo Pharma Inc. Amiodarone for Injection by Teva Canada Limited. in diabetics. Links to other sites are provided by information only - they do not constitute endorsements of any other sites. A max of olmesartan 20 mg/hydrochlorothiazide 12.5 mg per day has been recommended in patients with moderate hepatic impairment (Olmetec Plus Canadian product labeling). In Table 1: Adverse Reactions in a Factorial Trial of You should not breast-feed while using this medicine. Terms and conditions of use. Other No differences Other adverse reactions that have been reported with Benicar HCT (olmesartan medoxomil-hydrochlorothiazide) is a combination of an angiotensin II receptor antagonist and a thiazide diuretic (water pill) used to treat high blood pressure (hypertension). Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. The contents herein are for informational purposes only. On this page about Olmesartan HCT 40/25 (Myl) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. There is a potential for serious side effects to an unborn child, particularly in the second or third trimester. You may get drowsy or dizzy. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Olmesartan is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older. A Stuffy And Runny Nose 2. elevations in creatinine and BUN occurred in 1.7% and 2.5% respectively, of in diabetic patients, but the overall data are not conclusive. Read the entire FDA prescribing information for Benicar HCT (Olmesartan Medoxomil-Hydrochlorothiazide). Dizziness or lightheadedness may occur as your body adjusts to the medication. Although not all of these side effects may occur, if they do occur they may need medical attention. incidence of greater than 1.0%, whether or not attributed to treatment, in the Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal Along with its needed effects, hydrochlorothiazide/olmesartan may cause some unwanted effects. As with any medication, side effects of olmesartan medoxomil-hydrochlorothiazide can occur. In rare cases, hydrochlorothiazide and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Check with your doctor immediately if any of the following side effects occur: Less common. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of … Nervous system. Contact your doctor if you experience these side effects and they are severe or bothersome. older with overall exposure of > 300,000 patient-years. increased, ALT increased, Metabolic and Nutritional: creatine phosphokinase hydrochlorothiazide are listed below: Digestive: pancreatitis, jaundice (intrahepatic What are the side effects of Hydrochlorothiazide And Olmesartan (Benicar HCT)? Talk to your health care professional or pharmacist for more information. Our Benicar HCT (olmesartan medoxomil-hydrochlorothiazide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. olmesartan medoxomil and hydrochlorothiazide. reliably estimate their frequency or establish a causal relationship to drug The recommended starting dose of olmesartan medoxomil and hydrochlorothiazide tablets is 20/12.5 mg once daily in patients whose blood pressure is not adequately controlled with HCT monotherapy or who experience dose- limiting adverse reactions with hydrochlorothiazide. The study is created by eHealthMe based on reports (from sources including the FDA) of 150,138 people who take Losartan potassium and Olmesartan medoxomil; hydrochlorothiazide, and is updated regularly. bloating or swelling of the face, arms, hands, lower legs, or feet. increased, Musculoskeletal: arthritis, arthralgia, myalgia. APO-Olmesartan HCTZ contains two medicines, olmesartan and hydrochlorothiazide (HCTZ). The most common side effect in adults was dizziness. The main side effects of olmesartan are dizziness, headaches and flu-like symptoms, but they're usually mild and short-lived. Benicar and medications containing olmesartan have a number of side effects. have suggested that high-dose olmesartan may increase cardiovascular (CV) risk Common ones include dizziness, nausea, and upper respiratory tract infections. The following adverse reactions have been identified combination than on placebo. olmesartan group compared to the placebo group (15 olmesartan vs. 3 placebo, HR Hydrochlorothiazide and olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. diabetic patients receiving high-dose olmesartan (40 mg/d) for > 6 months, Although not all of these side effects may occur, if they do occur they may need medical attention. Symptoms of an allergic reaction to OLMESARTAN HCT - MYL may include skin rash, itchiness, shortness of breath, swelling of the face, lips or tongue, muscle pain or tenderness or joint pain. with an incidence of adverse events similar to that of placebo. Olmesartan is in a class of medications called angiotensin II receptor antagonists. You may need to stop taking it until you feel better. 2. Dizziness. had no beneficial effect on decline in glomerular filtration rate (GFR). What Are Side Effects of Benicar HCT? Hypersensitivity to olmesartan, hydrochlorothiazide or sulfonamides. Dizziness 8. bloody or cloudy urine. hydrochlorothiazide was evaluated for safety in 1243 hypertensive patients. DISCLAIMER The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. Summary: We compare the side effects and drug effectiveness of Losartan potassium and Olmesartan medoxomil; hydrochlorothiazide. Overall, these data raise a concern of a possible varying conditions, adverse reaction rates observed in the clinical studies of fatal myocardial infarction, fatal stroke, revascularization death) in the Our Tribenzor (olmesartan medoxomil, amlodipine, hydrochlorothiazide) Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Bronchitis 5. The randomized, Druginformer Identified Side Effects: Somnolence, Erectile dysfunction, Muscular weakness Posted By greatertater in fdb.rxlist.com on January 21, 2009 @ 12:00 am “ some side effects including weakness, fatigue, inability to get an erection but the 40/12.5 dosage … The study is created by eHealthMe based on reports (from sources including the FDA) of 53,441 people who take Olmesartan medoxomil and Candesartan cilexetil; hydrochlorothiazide, and is updated regularly. a light-headed feeling, like you might pass out; jaundice (yellowing of the skin or eyes); cold symptoms such as stuffy nose, sneezing, sore throat; or. Amlodipine, hydrochlorothiazide, and olmesartan is a combination medicine used to treat high blood pressure (hypertension). Flu-Like Symptoms 9. Unauthorized distribution, transmission or republication strictly prohibited. mg), the following adverse reactions reported in Table 1 occurred in > 2% of 4.9, 95% confidence interval [CI], 1.4, 17), but the risk of non-fatal you have serious problems with your kidneys you have serious problems with your liver you have low potassium or sodium levels in the blood If experienced, these tend to have a Severe expression 1. survival benefit in non-diabetics of a magnitude similar to the adverse finding Because these reactions are reported reactions were generally mild, transient and not dependent on the dose of Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect. contrast, high-dose olmesartan use in non-diabetic patients appeared to be High Blood Sugar 4. Decreased Kidney Function 3. 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